A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
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7.2 /10
397561 people rated
The Substance
2024
R
2 h 21 m
United Kingdom
Drama
Horror
Sci-Fi
A fading celebrity takes a black-market drug: a cell-replicating substance that helps her create a younger, better version of herself.
More
7.2 /10
397561 people rated
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Episodes
Top Cast
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Episodes
film
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Netflix
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Top Cast(19)
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Assistant Casting Director
Jiselle Henderkott
Girl Auditioning
Jiselle Henderkott
Dancer - New Year's Eve Show
Akil Wingate
TV Host
Billy Bentley
Man in Suit #1 - Harvey's Office
Vincent Colombe
Man in Suit #2
Lennard Ridsdale
Man in Suit #3
Jordan Ford Silver
Assistant Director - Pump It Up Show
User Review
Sohail khan Sarki king
05/03/2026 18:00
lora
Junior Musk
03/03/2026 12:35
hi
Rajesh Kumar
21/02/2026 14:29
www
M4RK1C08
20/02/2026 18:56
kepompong🙂↕️
Mustakim Billa
24/01/2026 17:24
, 🤭🥵🧐
Sanju Sharma
31/12/2025 15:55
hi
Naveed
26/12/2025 13:38
Hindi dubbed kro
Naveed
24/12/2025 17:43
Hindi dubbed kro
Meerub Hareem
28/11/2025 08:52
i want this movie in hindi
Ben ten
28/11/2025 08:09
a306mp
User Review
Sohail khan Sarki king
05/03/2026 18:00
lora
Junior Musk
03/03/2026 12:35
hi
Rajesh Kumar
21/02/2026 14:29
www
M4RK1C08
20/02/2026 18:56
kepompong🙂↕️
Mustakim Billa
24/01/2026 17:24
, 🤭🥵🧐
Sanju Sharma
31/12/2025 15:55
hi
Naveed
26/12/2025 13:38
Hindi dubbed kro
Naveed
24/12/2025 17:43
Hindi dubbed kro
Meerub Hareem
28/11/2025 08:52
i want this movie in hindi
Ben ten
28/11/2025 08:09
a306mp
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